573-882-4501
W106 Vet Med Bldg
University of Missouri
Columbia, MO 65211
Lab Information:
W-165
573-884-5577
Members:
Jennifer Casati, HT, HTL
E-130-132 573-884-9279
Cherie Chapman, HT, HTL
Marilyn Beissenherz, HT, HTL
Sandra Turner, HT
Matthew Roark, HT
Candace Utterback, HT
Research Interests:
Dr. Turk's research focus is the pathologic
evaluation of spontaneous and experimental
cardiopulmonary disease in domestic animals.
Current NIH-funded studies include the effects
of exercise on diet-induced atherosclerosis
in swine and the effects of exercise
on skeletal muscle vascular supply in rats.
Dr. Turk provides histopathologic and immunohistochemical
support for myriad studies of cardiovascular,
respiratory, and neoplastic diseases.
Teaching:
VPB5577 Veterinary Systemic
and Special Pathology II – Cardiovascular
and Respiratory Diseases
VPB6647 Diagnostic Pathology
and Special Species Medicine I - Cardiovascular
and Respiratory Diseases, Diseases of Swine,
Diseases of Cattle
VPB8436 Pathogenic Mechanisms
in Veterinary Pathobiology - Angiogenesis
Awards:
Pfizer Award for Research Excellence,
University of Missouri, College of Veterinary
Medicine, 2005
Gold Chalk Award, University of Missouri,
Graduate and Professional Student Council,
2002.
Golden Aesculapius Award, VM II, University
of Missouri, College of Veterinary Medicine,
1999.
Gold Chalk award from the University of
Missouri, Graduate and Professional Student
Council, 1999.
Norden Distinguished Teacher Award, University
of Missouri, College of Veterinary Medicine,
1997.
Merck Award for Creativity in Teaching,
University of Missouri, College of Veterinary
Medicine, 1996.
Golden Aesculapius Award, VM II, University
of Missouri, College of Veterinary Medicine,
1996.
Norden Distinguished Teaching in the Field
of Veterinary Medicine, Louisiana State
University, School of Veterinary Medicine,
1984.
Golden Aesculapius Award, University of
Missouri, College of Veterinary Medicine,
2004.
Professional Activities:
Manuscript review American Journal of Veterinary
Research (Amercian Veterinary Medical Assocation)
Manuscript review Cardiovascular Research
(European Society of Cardiology)
Manuscript review Hypertension (American
Heart Association)
Manuscript review Journal of Applied Physiology
(American Physiological Society)
Manuscript review Journal of the American
Veterinary Medical Association (American
Veterinary Medical Association)
Manuscript review Journal of Veterinary
Diagnostic Investigation (American Association
of Veterinary Laboratory Diagnosticians)
Manuscript review Journal of Zoo and Wildlife
Medicine (American Association of Zoo Veterinarians)
Manuscript review Medicine and Science
in Sports and Exercise (American College
of Sports Medicine)
Manuscript review Veterinary Pathology
(American Association of Veterinary Pathologists)
Publications:
Turk JR: Leading Edge of Medicine. Physiologic
and pathophysiologic effects of endothelin:
implications in cardiopulmonary disease.
J Am Vet Med Assoc 212:265-270,1998.
Turk JR: Reference Point. Physiologic and
pathophysiologic effects of natriuretic
peptides: implications in cardiopulmonary
disease. J Am Vet Med Assoc. 216:1970-1976,2000.
Woodman CR, Turk JR, Rush JWE, Laughlin
MH: Exercise attenuates the effects of hypercholesterolemia
on endothelium-dependent relaxation in coronary
arteries from adult female pigs. J Appl
Physiol 96:1105-1113, 2004.
Glinskii OV, Turk JR, Pienta KJ, Huxley
VH, Glinsky VV: Evidence of porcine and
human endothelium activation by cancer-associated
carbohydrates expressed on glycoproteins
and tumor cells. Journal of Physiology 554:89-99,2004.
Thompson MA, Henderson KK, Woodman CR,
Turk JR, Rush JWE, Price E, Laughlin MH.
Exercise Preserves Endothelium-Dependent
Relaxation in Coronary Arteries of Hypercholesterolemic
Male Pigs. Journal of Applied Physiology.
96:1114-1126, 2004.
Bowles DK, Heaps CL, Turk JR, Maddali KK,
Price EM. Hypercholesterolemia inhibits
L-type calcium current in coronary macro-,
not microcirculation. J Appl Physiol. 96:2240-2248,
2004.
Henderson KK, Turk JR, Rush JW, Laughlin
MH. Endothelial function in coronary arterioles
from pigs with early stage coronary disease
induced by high fat/cholesterol diet: effect
of exercise. J Appl Physiol. 97:1159 1168,2004.
Bowles DK, Maddali KK, Ganjam VK, Rubin
LJ, Tharp DL, Turk JR, Heaps CL. Endogenous
testosterone increases L-type Ca2+ channel
expression in porcine coronary smooth muscle.
Am J Physiol Heart Circ Physiol. 287:2091-2098,2004.
Morandi F, Mattoon JS, Lakritz J, Turk
JR, JQ Jaeger JQ,Wisner ER: Quantitative
evaluation of an acute inflammatory response
of the canine lung: correlation between
helical and incremental high-resolution
thin-section pulmonary computed tomography
and histomorphometry. Am J Vet Res. 65:1114-1123,
2004.
Turk JR, Laughlin MH: Physical activity
and atherosclerosis: which animal model?
Invited review Canadian Journal of Applied
Physiology. 29: 657-683, 2004.
Ray BK, Shakya A, Turk JR, Apte SS, Ray
A. Induction of the MMP-14 Gene in Macrophages
of the Atherosclerotic Plaque. Role of SAF-1
in the Induction Process. Circ Res. 95:1082-1090,
2004.
Maddali KK Korzick DH, Turk JR, Bowles
DK: Isoform-specific modulation of coronary
artery PKC by glucocorticoids. Vascular
Pharmacology 42:153-162,2005.
McAllister RM Albarracin I Price EM, Smith
TK, Turk JR Wyatt KD: Thyroid status and
nitric oxide in rat arterial vessels. J
Endocrinol 185:111-119,2005
Woodman CR, Thompson MA, Turk JR, Laughlin
MH: Endurance exercise training improves
endothelium-dependent relaxation in brachial
arteries from hypercholesterolemic male
pigs. J Appl Physiol, 2005. Jun 23; [Epub
ahead of print]
Turk JR, Henderson KK, Vanvickle GD, Watkins
JT, Laughlin MH: Arterial Endothelial Function
in a Porcine Model of Early Stage Atherosclerotic
Vascular Disease. International Journal
of Experimental Pathology, 86: 2005.
James
R. Turk, DVM, PhD